Hi John,
You have to create a connector and set the connection type as HDB (HANA Database) in Maintain Connectors and Connection Types first. Make sure you have HANA database plug-in installed as mentioned in GRC 10.1 installation guide which will enable Access controls to run with SAP HANA as DB and optimizes some of the High volume processes to take advantage of SAP HANA.
SAP HANA user provisioning to use SAP HANA-based applications.
Access to assignment of users on SAP HANA (Analytical Privileges and Roles)
Perform risk analysis for SAP HANA-based authorizations to avoid SoD conflicts
Using GRC 10.1 on HANA platform will help immensly mainly for ARA (access risk analysis)
SAP Access Control 10.1 has been enhanced and expanded. It now comes with a common standard ABAP platform leveraging SAP NetWeaver 7.40 SP 02 that provides the option to run on the SAP HANA database.
In nutshell, the best advantage of running GRC applications is, Reporting will be faster so would be the outputs.
You can refer:1869912 - SAP GRC 10.1 Plug-In SAP HANA, SAP HANA Content
Regards,
Madhu